Ligand-Controlled Asymmetric Arylation of Aliphatic α-Amino Anion Equivalents
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Zhu-2014-Ligand-controlled.pdf
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Author(s)
Zhu, Ye
Buchwald, Stephen Leffler
Date Issued
March 2014
Journal
Journal of the American Chemical Society
Publisher
American Chemical Society (ACS)
Citation
Zhu, Ye, and Stephen L. Buchwald. “Ligand-Controlled Asymmetric Arylation of Aliphatic α-Amino Anion Equivalents.” Journal of the American Chemical Society 136, no. 12 (March 26, 2014): 4500–4503. © 2014 American Chemical Society
Version
Final published version
Abstract
A palladium-catalyzed asymmetric arylation of 9-aminofluorene-derived imines using a chiral dialkylbiaryl phosphine as the supporting ligand has been developed. This transformation allows for enantioselective access to a diverse range of α-branched benzylamines.
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1021/ja501560x
