A microfluidic device to control bio actuators of microorganisms, an application to Vorticella convallaria
Name
Nagai-2009-A microfluidic device to control bio actuators of microorganisms, an application to Vorticella convallaria.pdf
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4.35 MB
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Adobe PDF
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Author(s) • • • •
Matsudaira, Paul T.
Ryu, Sangjin
Thorsen, Todd A.
Nagai, M.
Fujita, H.
Date Issued
June 2009
Journal
International Conference on Solid-State Sensors, Actuators, and Microsystems.
Publisher
Institute of Electrical and Electronics Engineers
Citation
Nagai, M. et al. “A microfluidic device to control bio actuators of microorganisms, an application to Vorticella convallaria.” Solid-State Sensors, Actuators and Microsystems Conference, 2009. TRANSDUCERS 2009. International. 2009. 437-440. © 2009, IEEE
Version
Final published version
Abstract
We demonstrate a microfluidic device to control the motion of Vorticella convallaria by changing solution. Floating cells of V. convallaria were injected and cultured inside the device. Approximately 35 cells of V. convallaria in 102 nl of the solution. The cells were treated with saponin solution and controlled with a microfluidic device. When reaction solution was switched, the stalk contracted and relaxed corresponding to the ambient calcium ion concentration change. The length of the stalk changed between 40 and 60 mum, resulting in a working distance of about 20 mum.
MIT Department
Massachusetts Institute of Technology. Department of Biological Engineering
Massachusetts Institute of Technology. Department of Mechanical Engineering
Whitehead Institute for Biomedical Research
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1109/SENSOR.2009.5285468