Sequential immunization of macaques elicits heterologous neutralizing antibodies targeting the V3-glycan patch of HIV-1 Env
Name
nihms-1786406.pdf
Description
Accepted version
Size
3.37 MB
Format
Adobe PDF
Checksum (MD5)
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Author(s)
Escolano, Amelia
Gristick, Harry B
Gautam, Rajeev
DeLaitsch, Andrew T
Abernathy, Morgan E
Yang, Zhi
Wang, Haoqing
Hoffmann, Magnus AG
Nishimura, Yoshiaki
Wang, Zijun
Date Issued
2021
Journal
Science Translational Medicine
Publisher
American Association for the Advancement of Science (AAAS)
Citation
Escolano, Amelia, Gristick, Harry B, Gautam, Rajeev, DeLaitsch, Andrew T, Abernathy, Morgan E et al. 2021. "Sequential immunization of macaques elicits heterologous neutralizing antibodies targeting the V3-glycan patch of HIV-1 Env." Science Translational Medicine, 13 (621).
Version
Author's final manuscript
Abstract
Sequential immunization elicits antibodies against the V3-glycan patch of HIV-1 Env in rhesus macaques and also induces off-target antibody responses.
MIT Department
Massachusetts Institute of Technology. Department of Biological Engineering
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Creative Commons Attribution-Noncommercial-Share Alike
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DOI of Published Version
https://doi.org/10.1126/SCITRANSLMED.ABK1533
