Programmable Medicine: Autonomous, Ingestible, Deployable Hydrogel Patch and Plug for Stomach Ulcer Therapy
Name
ICRA18_0684_FI.pdf
Description
Accepted version
Size
1.71 MB
Format
Adobe PDF
Checksum (MD5)
97152d3fae9d0d39797c85e3a58ebfb4
Author(s)
du Plessis d'Argentre, Alexis
Perry, Samuel
Iwata, Yoshitaka
Iwasaki, Haruna
Iwase, Eiji
Fabozzo, Assunta
Will, Iain
Rus, Daniela
Damian, Dana D.
Miyashita, Shuhei
Date Issued
May 2018
Publisher
IEEE
Citation
du Plessis d'Argentre, Alexis, Perry, Samuel, Iwata, Yoshitaka, Iwasaki, Haruna, Iwase, Eiji et al. 2018. "Programmable Medicine: Autonomous, Ingestible, Deployable Hydrogel Patch and Plug for Stomach Ulcer Therapy."
Version
Author's final manuscript
Abstract
© 2018 IEEE. Gastric ulcer is a chronic and complex (and often complete) erosion of the stomach wall that happens as a complication of a previous chronic, inflammatory process. It represents a catastrophic situation in which the patient is critical and its conditions need to be treated fast. This study presents a remotely navigatable and deployable ingestible patch and plug for gastric ulcer treatment. The patch/plug structure is made of agarose hydrogel that can change rigidity through hydration and dehydration. When dehydrated, it is rigid and can maintain a folded configuration so it can be ingested as a 'pill'. This can be guided to the targeted location by a magnetic field, and be deployed instantly by hydration, namely by supplying water from the mouth. Due to the deployable origami design, it exhibits an expansion of 10 times its initial surface area, making the device suitable for the use of dressing a surface as a patch, and filling a hole as a plug.
MIT Department
Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Terms of Use
Creative Commons Attribution-Noncommercial-Share Alike
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1109/icra.2018.8460615
