Design and optimization of a nozzle for a needle-free injection system
Name
62776203-MIT.pdf
Description
Full printable version
Size
1.72 MB
Format
Adobe PDF
Checksum (MD5)
06a235f64e32da05c170a00fd221f791
Author(s)
Sanchez, Gabriel Nestor
Advisor(s)
Ian W. Hunter.
Alternative Title
Nozzle for a needle-free injection system
Date Issued
2005
Publisher
Massachusetts Institute of Technology
Abstract
The purpose of this thesis was to develop an optimized nozzle for the needle-free injection device currently under construction in MIT's Bio-Instrumentation Laboratory. Initial predictions from ANSYS, a finite element modeling program, indicated that the injection performance could be noticeably improved with a new nozzle design. After running several flow simulations, a final nozzle design was selected, and a strategy was developed to manufacture the new nozzle. The new nozzle was placed in the injection device and measurements of the jet velocity were recorded via a high speed camera. A 2mm long nozzle with a contoured profile consisting of a linear segment tangent to an arc segment at the nozzle exit produced an exit velocity of 45.5m/s at the end of the injection stroke. This showed almost a 19 percent increase in velocity compared to the older nozzle which produced 38. lm/s upon termination of the injection cycle. However, the results of the new nozzle vary from injection to injection. Thus there is a need for continued testing in the future, and possibly more refined measuring techniques such as depth of penetration into the gel or developing improvements with the current video setup.
Description
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, June 2005.
Includes bibliographical references (leaf 33).
Subjects
Mechanical Engineering.
MIT Department
Massachusetts Institute of Technology. Department of Mechanical Engineering
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