HeLiVa platform: integrated heart-liver-vascular systems for drug testing in human health and disease
Name
document.pdf
Description
Published version
Size
1.96 MB
Format
Adobe PDF
Checksum (MD5)
f7ee8f981e2a774d8bda0879cefc41b4
Author(s)
Vunjak-Novakovic, Gordana V
Bhatia, Sangeeta N
Chen, Christopher
Hirschi, Karen
Date Issued
2013
Journal
Stem Cell Research & Therapy
Publisher
Biomed Central Ltd.
Citation
Vunjak-Novakovic, Gordana, et al. “HeLiVa Platform: Integrated Heart-Liver-Vascular Systems for Drug Testing in Human Health and Disease.” Stem Cell Research & Therapy, vol. 4, no. Suppl 1, 2013, p. S8. © 2010 BioMed Central Ltd.
Version
Final published version
Abstract
Our project team is developing an integrated microphysiological platform with functionally connected vascular, liver and cardiac microtissues derived from a single line of human pluripotent stem cells. The platform enables functional representation of human physiology in conjunction with real-time biological readouts (via imaging and homologous reporters for all three cell phenotypes) and compatibility with high-throughput/high-content analysis. In this paper, we summarize progress made over the first year of the grant. Keywords: Vioxx, Glycol Diacrylate, Genotype Pool, Tissue Module, Polyethylene Glycol Diacrylate
MIT Department
Harvard University--MIT Division of Health Sciences and Technology
Terms of Use
Creative Commons Attribution 4.0 International license
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1186/SCRT369
