Synthetic communities, the sum of parts
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TeagueWeiss2015.pdf
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Author(s)
Teague, Brian Paul
Weiss, Ron
Alternative Title
Synthetic communities, the sum of parts
Date Issued
August 2015
Journal
Science
Publisher
American Association for the Advancement of Science (AAAS)
Citation
Teague, B. P. and Weiss, R. “Synthetic Communities, the Sum of Parts.” Science 349, no. 6251 (August 2015): 924–925. © 2015 American Association for the Advancement of Science
Version
Original manuscript
Abstract
Cooperation between cells is one of evolution's fundamental innovations. It allows cells to specialize: Different members of a consortium assume different responsibilities, increasing overall productivity and allowing for more complex behavior than is possible with a single cell or a monoculture (1). These features of natural systems have attracted the attention of synthetic biologists, who have made engineering of cooperation between cells a long-standing goal. On page 986 of this issue, Chen et al. (2) report the creation of a synthetic consortium of cooperating Escherichia coli bacteria. The design principles they demonstrate have important implications for the construction of multicellular synthetic systems.
MIT Department
Massachusetts Institute of Technology. Department of Biological Engineering
Massachusetts Institute of Technology. Research Laboratory of Electronics
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1126/science.aad0876
