Microgels for Efficient Protein Purification
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nihms582990.pdf
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Accepted version
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Author(s) • • • • • • •
Mizrahi, Boaz
Irusta, Silvia
McKenna, Marshall
Stefanescu, Cristina
Yedidsion, Liron
Myint, MyatNoeZin
Langer, Robert
Kohane, Daniel S
Date Issued
2011
Journal
Advanced Materials
Publisher
Wiley
Citation
Mizrahi, B., et al. "Microgels for Efficient Protein Purification." Adv Mater (2011).
Version
Author's final manuscript
Abstract
Microgel particles with pore structure and ligands distributed evenly throughout their matrices overcome the major limitations of protein purification systems: low ligand density on the immobilized matrix and protein access to those ligands. A straightforward synthetic scheme for a highly efficient microgel matrix is reported. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
MIT Department
Massachusetts Institute of Technology. Department of Chemical Engineering
Massachusetts Institute of Technology. Operations Research Center
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Creative Commons Attribution-Noncommercial-Share Alike
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DOI of Published Version
https://doi.org/10.1002/adma.201101258