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Cerebellar Contributions to Social Cognition in ASD: A Predictive Processing Framework
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fnint-16-810425.pdf
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1.21 MB
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Unknown
Checksum (MD5)
dbd10bf02e4ca44683ddf57b0657fe61
Author(s)
Frosch, Isabelle R.
Mittal, Vijay A.
D’Mello, Anila M.
Date Issued
January 2022
Journal
Frontiers in Integrative Neuroscience
Publisher
Frontiers Media SA
Citation
Frosch, Isabelle R., Mittal, Vijay A. and D’Mello, Anila M. 2022. "Cerebellar Contributions to Social Cognition in ASD: A Predictive Processing Framework." Frontiers in Integrative Neuroscience, 16.
Abstract
Functional, structural, and cytoarchitectural differences in the cerebellum are consistently reported in Autism Spectrum Disorders (ASD). Despite this, the mechanisms governing cerebellar contributions to ASD, particularly within the sociocognitive domain, are not well understood. Recently, it has been suggested that several core features of ASD may be associated with challenges creating and using prior expectations or predictions to rapidly adapt to changing stimuli or situations, also known as adaptive prediction. Importantly, neuroimaging, clinical, and animal work find that the cerebellum supports adaptive prediction in both motor and non-motor domains. Perturbations to the cerebellum via injury or neuromodulation have been associated with impairments in predictive skills. Here, we review evidence for a cerebellar role in social cognition and adaptive prediction across individuals with and without ASD.
Terms of Use
Creative Commons Attribution 4.0 International license
Persistent DSpace Link
DOI of Published Version
http://dx.doi.org/10.3389/fnint.2022.810425
