Bioinspired chemistry at MOF secondary building units
Name
c9sc06418d.pdf
Description
Published version
Size
1.1 MB
Format
Adobe PDF
Checksum (MD5)
3e47001fb63007f23aa7b0b60f64c955
Author(s)
Bour, James R.
Wright, Ashley Michael
He, Xin
Dinca, Mircea
Date Issued
January 2020
Journal
Chemical Science
Publisher
Royal Society of Chemistry (RSC)
Citation
Bour, James R. et al. "Bioinspired chemistry at MOF secondary building units." Chemical Science 11, 7 (January 2020): 1728-1737 © The Royal Society of Chemistry
Version
Final published version
Abstract
The secondary building units (SBUs) in metal-organic frameworks (MOFs) support metal ions in well-defined and site-isolated coordination environments with ligand fields similar to those found in metalloenzymes. This burgeoning class of materials has accordingly been recognized as an attractive platform for metalloenzyme active site mimicry and biomimetic catalysis. Early progress in this area was slowed by challenges such as a limited range of hydrolytic stability and a relatively poor diversity of redox-active metals that could be incorporated into SBUs. However, recent progress with water-stable MOFs and the development of more sophisticated synthetic routes such as postsynthetic cation exchange have largely addressed these challenges. MOF SBUs are being leveraged to interrogate traditionally unstable intermediates and catalytic processes involving small gaseous molecules. This perspective describes recent advances in the use of metal centers within SBUs for biomimetic chemistry and discusses key future developments in this area.
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
Terms of Use
Creative Commons Attribution Noncommercial 3.0 unported license
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1039/c9sc06418d
