A Silent Operon of Photorhabdus luminescens Encodes a Prodrug Mimic of GTP
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mbio.00700-22.pdf
Description
Published version
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2.19 MB
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Checksum (MD5)
5b322a9584894b864e9db5b8473ddbb3
Author(s)
Shahsavari, Negar
Wang, Boyuan
Imai, Yu
Mori, Miho
Son, Sangkeun
Liang, Libang
Böhringer, Nils
Manuse, Sylvie
Gates, Michael F
Morrissette, Madeleine
Date Issued
2022
Journal
mBio
Publisher
American Society for Microbiology
Citation
Shahsavari, Negar, Wang, Boyuan, Imai, Yu, Mori, Miho, Son, Sangkeun et al. 2022. "A Silent Operon of Photorhabdus luminescens Encodes a Prodrug Mimic of GTP." mBio, 13 (3).
Version
Final published version
Abstract
Drug-resistant Gram-negative bacteria have become the major problem driving the antimicrobial resistance crisis. Searching outside the overmined actinomycetes, we focused on Photorhabdus , gut symbionts of enthomopathogenic nematodes that carry up to 40 biosynthetic gene clusters coding for secondary metabolites.
Drug-resistant Gram-negative bacteria have become the major problem driving the antimicrobial resistance crisis. Searching outside the overmined actinomycetes, we focused on Photorhabdus , gut symbionts of enthomopathogenic nematodes that carry up to 40 biosynthetic gene clusters coding for secondary metabolites.
MIT Department
Massachusetts Institute of Technology. Department of Biology
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Creative Commons Attribution 4.0 International license
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DOI of Published Version
https://doi.org/10.1128/MBIO.00700-22
