Perspective: The promise of multi-cellular engineered living systems
Name
1.5038337.pdf
Description
Published version
Size
2.07 MB
Format
Adobe PDF
Checksum (MD5)
e672e36a59094499b65759439d0138b5
Author(s)
Kamm, Roger D.
Arora, Natasha
Griffith, Linda G.
Martin, Adam C.
Weiss, Ron
Yevick, Hannah G.
Zaman, Muhammed H.
Date Issued
October 2018
Journal
APL bioengineering
Publisher
AIP Publishing
Citation
Kamm, Roger D. et al. “Perspective: The promise of multi-cellular engineered living systems.” APL bioengineering 2 (2018): 040901 © 2018 The Author(s)
Version
Final published version
Abstract
Recent technological breakthroughs in our ability to derive and differentiate induced pluripotent stem cells, organoid biology, organ-on-chip assays, and 3-D bioprinting have all contributed to a heightened interest in the design, assembly, and manufacture of living systems with a broad range of potential uses. This white paper summarizes the state of the emerging field of "multi-cellular engineered living systems," which are composed of interacting cell populations. Recent accomplishments are described, focusing on current and potential applications, as well as barriers to future advances, and the outlook for longer term benefits and potential ethical issues that need to be considered.
MIT Department
Massachusetts Institute of Technology. Department of Biological Engineering
Massachusetts Institute of Technology. Department of Biology
Terms of Use
Creative Commons Attribution 4.0 International license
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1063/1.5038337
