The complementary roles of dynamic contrast-enhanced MRI and [supersript 18]F-fluorodeoxyglucose PET/CT for imaging of carotid atherosclerosis
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Author(s)
Calcagno, Claudia
Ramachandran, Sarayu
Mani, Venkatesh
Millon, Antoine
Rosenbaum, David
Tawakol, Ahmed
Woodward, Mark
Bucerius, Jan
Moshier, Erin
Godbold, James
Alternative Title
The complementary roles of dynamic contrast-enhanced MRI and 18F-fluorodeoxyglucose PET/CT for imaging of carotid atherosclerosis
Date Issued
August 2013
Journal
European Journal of Nuclear Medicine and Molecular Imaging
Publisher
Springer Berlin Heidelberg
Citation
Calcagno, Claudia et al. “The Complementary Roles of Dynamic Contrast-Enhanced MRI and 18F-Fluorodeoxyglucose PET/CT for Imaging of Carotid Atherosclerosis.” European Journal of Nuclear Medicine and Molecular Imaging 40.12 (2013): 1884–1893.
Version
Author's final manuscript
Abstract
Inflammation and neovascularization in vulnerable atherosclerotic plaques are key features for severe clinical events. Dynamic contrast-enhanced (DCE) MRI and FDG PET are two noninvasive imaging techniques capable of quantifying plaque neovascularization and inflammatory infiltrate, respectively. However, their mutual role in defining plaque vulnerability and their possible overlap has not been thoroughly investigated. We studied the relationship between DCE-MRI and [supersript 18]F-FDG PET data from the carotid arteries of 40 subjects with coronary heart disease (CHD) or CHD risk equivalent, as a substudy of the dal-PLAQUE trial (NCT00655473).
MIT Department
Martinos Imaging Center (McGovern Institute for Brain Research at MIT)
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1007/s00259-013-2518-4
