Translation Initiation Site Profiling Reveals Widespread Synthesis of Non-AUG-Initiated Protein Isoforms in Yeast
Name
1-s2.0-S2405471220302404-main.pdf
Description
Published version
Size
3.47 MB
Format
Adobe PDF
Checksum (MD5)
db7bbfcd0448ee20b8ee066b4fd1866b
Author(s)
Eisenberg, Amy R
Higdon, Andrea L
Hollerer, Ina
Fields, Alexander P
Jungreis, Irwin
Diamond, Paige D
Kellis, Manolis
Jovanovic, Marko
Brar, Gloria A
Date Issued
2020
Journal
Cell Systems
Publisher
Elsevier BV
Version
Final published version
Abstract
© 2020 The Authors Eisenberg et al. identify translation initiation sites genome-wide in budding yeast. They define a class of 149 genes with alternate extended isoforms that initiate at non-AUG start codons. These isoforms are produced in concert with their corresponding canonical isoforms but typically at lower abundance, and are selectively induced during meiosis.
MIT Department
Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Terms of Use
Creative Commons Attribution-NonCommercial-NoDerivs License
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1016/J.CELS.2020.06.011
