An Electronic Force Sensor for Medical Jet Injection
Name
med_013_02_021007.pdf
Description
Published version
Size
4.25 MB
Format
Adobe PDF
Checksum (MD5)
373e633efcb0fe1c3096eb77e90d8c6b
Author(s)
Demas, Nickolas P
Hunter, Ian W
Date Issued
2019
Journal
Journal of Medical Devices
Publisher
ASME International
Version
Final published version
Abstract
© 2019 by ASME. In medical jet injection, a narrow fluid drug stream is propelled at high velocity into skin without a needle. Previous studies have shown that the volume delivered is highly dependent on a number of factors. This paper details the development of an electronic force sensor for medical jet injection and shows that the normal contact force exerted on the tissue by the nozzle is an additional factor affecting volume delivered. Using this sensor, we measure the forces at the nozzle tip in the normal direction with a sensitivity of 18 μN, calibrated over a range from 1 N to 8 N with a mean absolute error of 8 μN, and a maximum overload of 300 N. We further measure forces at the nozzle tip in the lateral direction with a sensitivity of 8 μN, calibrated over a range from 0.1 N to 7 N, with a mean absolute error of 101mN for lateral contact force magnitude and 1.60 deg for lateral contact force direction. Experimental validation confirms that the force sensor does not adversely affect the accuracy and precision of ejected volume from the jet injector. We use this setup to examine the effect of normal contact force on volume delivered into postmortem porcine tissue. Experimental results demonstrate that volume delivered with normal contact force between 4 N and 8 N is significantly more accurate and precise compared to volume delivered with normal contact force between 0N and 3.9 N.
MIT Department
Massachusetts Institute of Technology. Department of Mechanical Engineering
Terms of Use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1115/1.4043196
