The Tectorial Membrane: Mechanical Properties and Functions
Name
The_tectorial_membrane_Mechanical_properties_and_functions.pdf
Size
2.97 MB
Format
Adobe PDF
Checksum (MD5)
086711e9f74a4ae2ec76fad96c7bc8e5
Author(s)
Sellon, Jonathan Blake
Ghaffari, Roozbeh
Freeman, Dennis M
Date Issued
October 2018
Journal
Cold Spring Harbor Perspectives in Medicine
Publisher
Cold Spring Harbor Laboratory
Citation
Sellon, Jonathan et al. "The Tectorial Membrane: Mechanical Properties and Functions." Cold Spring Harbor Perspectives in Medicine Cold Spring Harbor 9 (October 2019): a033514 © 2019 Cold Spring Harbor Laboratory Press
Version
Author's final manuscript
Abstract
The tectorial membrane (TM) is widely believed to play a critical role in determining the remarkable sensitivity and frequency selectivity that are hallmarks of mammalian hearing. Recently developed mouse models of human hearing disorders have provided new insights into the molecular, nanomechanical mechanisms that underlie resonance and traveling wave properties of the TM. Herein we review recent experimental and theoretical results detailing TM morphology, local poroelastic and electromechanical interactions, and global spread of excitation via TM traveling waves, with direct implications for cochlear mechanisms.
MIT Department
Massachusetts Institute of Technology. Research Laboratory of Electronics
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Terms of Use
Creative Commons Attribution-Noncommercial-Share Alike
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1101/cshperspect.a033514
