Advances in Biomaterials for Drug Delivery
Name
nihms-996989.pdf
Description
Accepted version
Size
3.74 MB
Format
Adobe PDF
Checksum (MD5)
4788284fcf749585865f4a9850556dcc
Author(s) • • • •
Fenton, Owen Shea
Olafson, Katy
Pillai, Padmini S
Mitchell, Michael J.
Langer, Robert S
Date Issued
May 2018
Journal
Advanced Materials
Publisher
Wiley
Citation
Fenton, Owen S. et al. "Advances in Biomaterials for Drug Delivery." Advance Materials 30, 29 (May 2018): 1705328 © 2018 WILEY-VCH Verlag GmbH & Co
Version
Author's final manuscript
Abstract
Advances in biomaterials for drug delivery are enabling significant progress in biology and medicine. Multidisciplinary collaborations between physical scientists, engineers, biologists, and clinicians generate innovative strategies and materials to treat a range of diseases. Specifically, recent advances include major breakthroughs in materials for cancer immunotherapy, autoimmune diseases, and genome editing. Here, strategies for the design and implementation of biomaterials for drug delivery are reviewed. A brief history of the biomaterials field is first established, and then commentary on RNA delivery, responsive materials development, and immunomodulation are provided. Current challenges associated with these areas as well as opportunities to address long-standing problems in biology and medicine are discussed throughout.
MIT Department
Massachusetts Institute of Technology. Department of Chemical Engineering
Harvard University--MIT Division of Health Sciences and Technology
Koch Institute for Integrative Cancer Research at MIT
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Creative Commons Attribution-Noncommercial-Share Alike
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DOI of Published Version
https://doi.org/10.1002/adma.201705328