Photometric stereo endoscopy
Name
Parot-2013-Photometric stereo endoscopy.pdf
Size
5.54 MB
Format
Adobe PDF
Checksum (MD5)
e972c66a4cac6238db807851c7af6377
Author(s)
Parot, Vicente
Lim, Daryl
Gonzalez Serrano, German
Durr, Nicholas
Vakoc, Benjamin
Nishioka, Norman S.
Traverso, Carlo Giovanni
Date Issued
July 2013
Journal
Journal of Biomedical Optics
Publisher
SPIE
Citation
Parot, Vicente. “Photometric stereo endoscopy.” Journal of Biomedical Optics 18, no. 7 (July 1, 2013): 076017.
Version
Final published version
Abstract
While color video endoscopy has enabled wide-field examination of the gastrointestinal tract, it often misses or incorrectly classifies lesions. Many of these missed lesions exhibit characteristic three-dimensional surface topographies. An endoscopic system that adds topographical measurements to conventional color imagery could therefore increase lesion detection and improve classification accuracy. We introduce photometric stereo endoscopy (PSE), a technique which allows high spatial frequency components of surface topography to be acquired simultaneously with conventional two-dimensional color imagery. We implement this technique in an endoscopic form factor and demonstrate that it can acquire the topography of small features with complex geometries and heterogeneous optical properties. PSE imaging of ex vivo human gastrointestinal tissue shows that surface topography measurements enable differentiation of abnormal shapes from surrounding normal tissue. Together, these results confirm that the topographical measurements can be obtained with relatively simple hardware in an endoscopic form factor, and suggest the potential of PSE to improve lesion detection and classification in gastrointestinal imaging.
MIT Department
Harvard University--MIT Division of Health Sciences and Technology
Massachusetts Institute of Technology. Research Laboratory of Electronics
Koch Institute for Integrative Cancer Research at MIT
Terms of Use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1117/1.jbo.18.7.076017
