MIT Libraries logoDSpace@MIT

MIT
View Item 
  • DSpace@MIT Home
  • MIT Open Access Articles
  • MIT Open Access Articles
  • View Item
  • DSpace@MIT Home
  • MIT Open Access Articles
  • MIT Open Access Articles
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Results of late surgical intervention in children with early-onset bilateral cataracts

Author(s)
Ganesh, Suma; Arora, Priyanka; Sethi, Sumita; Gandhi, Tapan Kumar; Kalia, Amy Ashwin; Chatterjee, Garga; Sinha, Pawan; ... Show more Show less
Thumbnail
DownloadSinha_Results of late.pdf (404.5Kb)
OPEN_ACCESS_POLICY

Open Access Policy

Creative Commons Attribution-Noncommercial-Share Alike

Terms of use
Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/
Metadata
Show full item record
Abstract
Background Cataracts are a major cause of childhood blindness globally. Although surgically treatable, it is unclear whether children would benefit from such interventions beyond the first few years of life, which are believed to constitute ‘critical’ periods for visual development. Aims To study visual acuity outcomes after late treatment of early-onset cataracts and also to determine whether there are longitudinal changes in postoperative acuity. Methods We identified 53 children with dense cataracts with an onset within the first half-year after birth through a survey of over 20 000 rural children in India. All had accompanying nystagmus and were older than 8 years of age at the time of treatment. They underwent bilateral cataract surgery and intraocular lens implantation. We then assessed their best-corrected visual acuity 6 weeks and 6 months after surgery. Results 48 children from the pool of 53 showed improvement in their visual acuity after surgery. Our longitudinal assessments demonstrated further improvements in visual acuity for the majority of these children proceeding from the 6-week to 6-month assessment. Interestingly, older children in our subject pool did not differ significantly from the younger ones in the extent of improvement they exhibit. Conclusions and relevance Our results demonstrate that not only can significant vision be acquired until late in childhood, but that neural processes underlying even basic aspects of vision like resolution acuity remain malleable until at least adolescence. These data argue for the provision of cataract treatment to all children, irrespective of their age.
Date issued
2014-05
URI
http://hdl.handle.net/1721.1/102504
Department
Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Journal
British Journal of Ophthalmology
Publisher
BMJ Publishing Group
Citation
Ganesh, S., P. Arora, S. Sethi, T. K. Gandhi, A. Kalia, G. Chatterjee, and P. Sinha. “Results of Late Surgical Intervention in Children with Early-Onset Bilateral Cataracts.” British Journal of Ophthalmology 98, no. 10 (October 1, 2014): 1424–28.
Version: Author's final manuscript
ISSN
0007-1161

Collections
  • MIT Open Access Articles

Browse

All of DSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

My Account

Login

Statistics

OA StatisticsStatistics by CountryStatistics by Department
MIT Libraries
PrivacyPermissionsAccessibilityContact us
MIT
Content created by the MIT Libraries, CC BY-NC unless otherwise noted. Notify us about copyright concerns.