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dc.contributor.authorRuiz-Castillo, Paula
dc.contributor.authorBuchwald, Stephen Leffler
dc.date.accessioned2018-01-10T21:14:44Z
dc.date.available2018-01-10T21:14:44Z
dc.date.issued2016-09
dc.date.submitted2016-08
dc.identifier.issn0009-2665
dc.identifier.issn1520-6890
dc.identifier.urihttp://hdl.handle.net/1721.1/113056
dc.description.abstractPd-catalyzed cross-coupling reactions that form C-N bonds have become useful methods to synthesize anilines and aniline derivatives, an important class of compounds throughout chemical research. A key factor in the widespread adoption of these methods has been the continued development of reliable and versatile catalysts that function under operationally simple, user-friendly conditions. This review provides an overview of Pd-catalyzed N-arylation reactions found in both basic and applied chemical research from 2008 to the present. Selected examples of C-N cross-coupling reactions between nine classes of nitrogen-based coupling partners and (pseudo)aryl halides are described for the synthesis of heterocycles, medicinally relevant compounds, natural products, organic materials, and catalysts.en_US
dc.description.sponsorshipNational Institutes of Health (U.S.) (Award GM58160)en_US
dc.publisherAmerican Chemical Society (ACS)en_US
dc.relation.isversionofhttp://dx.doi.org/10.1021/ACS.CHEMREV.6B00512en_US
dc.rightsArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.en_US
dc.sourceACSen_US
dc.titleApplications of Palladium-Catalyzed C–N Cross-Coupling Reactionsen_US
dc.typeArticleen_US
dc.identifier.citationRuiz-Castillo, Paula and Buchwald, Stephen L. “Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions.” Chemical Reviews 116, 19 (September 2016): 12564–12649 © 2016 American Chemical Societyen_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Chemistryen_US
dc.contributor.mitauthorRuiz-Castillo, Paula
dc.contributor.mitauthorBuchwald, Stephen Leffler
dc.relation.journalChemical Reviewsen_US
dc.eprint.versionFinal published versionen_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dc.date.updated2018-01-10T16:14:20Z
dspace.orderedauthorsRuiz-Castillo, Paula; Buchwald, Stephen L.en_US
dspace.embargo.termsNen_US
dc.identifier.orcidhttps://orcid.org/0000-0002-5654-503X
dc.identifier.orcidhttps://orcid.org/0000-0003-3875-4775
mit.licensePUBLISHER_POLICYen_US


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