Cellular biophysical markers of hydroxyurea treatment in sickle cell disease

Author(s)
Du, E.; Papageorgiou, Dimitrios P.; Park, YongKeun; Higgins, John; Kato, Gregory J.; ... Show more
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Abstract
Using a common-path interferometric technique, we measure biomechanical and morphological properties of individual red blood cells in SCD patients as a function of cell density, and investigate the correlation of these biophysical properties with drug intake as well as other clinically measured parameters.
Date issued
2017-04
URI
http://hdl.handle.net/1721.1/115510
Department
Massachusetts Institute of Technology. Department of Biological Engineering; Massachusetts Institute of Technology. Department of Chemistry; Massachusetts Institute of Technology. Department of Mechanical Engineering; Massachusetts Institute of Technology. Laser Biomedical Research Center
Journal
Proceedings Volume 10251, Biomedical Imaging and Sensing Conference
Publisher
SPIE
Citation
So, Peter T. C., et al. "Cellular Biophysical Markers of Hydroxyurea Treatment in Sickle Cell Disease." Proceedings Volume 10251, Biomedical Imaging and Sensing Conference, 19-21 April, 2017, Yokohama, Japan, edited by Toyohiko Yatagai et al., SPIE, 2017, p. 1025103. © 2017 SPIE.
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