Show simple item record

dc.contributor.authorKou, Shan Shan
dc.contributor.authorSheppard, Colin J. R.
dc.contributor.authorLuo, Yuan
dc.contributor.authorOh, Se Baek
dc.contributor.authorLee, Justin Wu
dc.contributor.authorBarbastathis, George
dc.date.accessioned2018-11-02T17:19:38Z
dc.date.available2018-11-02T17:19:38Z
dc.date.issued2010-03
dc.identifier.urihttp://hdl.handle.net/1721.1/118840
dc.description.abstractWe present a theoretical formulation to quantify the imaging properties of volume holographic microscopy (VHM). Volume holograms are formed by exposure of a photosensitive recording material to the interference of two mutually coherent optical fields. Recently, it has been shown that a volume holographic pupil has spatial and spectral sectioning capability for fluorescent samples. Here, we analyze the point spread function (PSF) to assess the imaging behavior of the VHM with a point source and detector. The coherent PSF of the VHM is derived, and the results are compared with those from conventional microscopy, and confocal microscopy with point and slit apertures. According to our analysis, the PSF of the VHM can be controlled in the lateral direction by adjusting the parameters of the VH. Compared with confocal microscopes, the performance of the VHM is comparable or even potentially better, and the VHM is also able to achieve real-time and three-dimensional (3D) imaging due to its multiplexing ability. © 2010 SPIE.en_US
dc.publisherSPIEen_US
dc.relation.isversionofhttp://dx.doi.org/10.1117/12.844310en_US
dc.rightsArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.en_US
dc.sourceSPIEen_US
dc.titleImage formation of volume holographic microscopy using point spread functionsen_US
dc.typeArticleen_US
dc.identifier.citationLuo, Yuan, et al. "Image Formation of Volume Holographic Microscopy Using Point Spread Functions." Proceedings Volume 7622, Medical Imaging 2010: Physics of Medical Imaging, 15-18 March, 2010, San Diego, California, 2010, SPIE, p. 76224E. © 2010 Society of Photo-Optical Instrumentation Engineers (SPIE)en_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Mechanical Engineeringen_US
dc.contributor.mitauthorLuo, Yuan
dc.contributor.mitauthorOh, Se Baek
dc.contributor.mitauthorLee, Justin Wu
dc.contributor.mitauthorBarbastathis, George
dc.relation.journalProceedings Volume 7622, Medical Imaging 2010: Physics of Medical Imagingen_US
dc.eprint.versionFinal published versionen_US
dc.type.urihttp://purl.org/eprint/type/ConferencePaperen_US
eprint.statushttp://purl.org/eprint/status/NonPeerRevieweden_US
dc.date.updated2018-10-26T17:28:30Z
dspace.orderedauthorsLuo, Yuan; Oh, Se Baek; Kou, Shan Shan; Lee, Justin; Sheppard, Colin J. R.; Barbastathis, Georgeen_US
dspace.embargo.termsNen_US
dc.identifier.orcidhttps://orcid.org/0000-0002-7225-7580
dc.identifier.orcidhttps://orcid.org/0000-0002-4140-1404
mit.licensePUBLISHER_POLICYen_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record