The digital symbol digit test : screening for Alzheimer's and Parkinson's
Author(s)Huang, Lauren(Lauren A.)
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science.
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Neurodegenerative diseases affect the cognition of millions of people worldwide, degrading their quality of life and placing a burden on their families. Early identication can be extremely beneficial in treating or slowing down the onset of these diseases. One technique used to identify early warning signs is the use of cognitive tests. Unfortunately, grading these tests is subjective. In this study, we quantitatively evaluated the digital Symbol Digit Test (dSDT), in which patients translate symbols into digits based on a given mapping. In collaboration with Dr. Penney of Lahey Clinic, we administered the dSDT to over 170 patients using a digitizing pen that measures its position on the page and the pressure applied. We developed support vector machine and logistic regression classifiers that indicate Alzheimer's Disease and Parkinson's Disease with an area under the curve of 0.957 and 0.963, respectively.
This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Thesis: M. Eng., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 2017Cataloged from student-submitted PDF version of thesis.Includes bibliographical references (pages 81-82).
DepartmentMassachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Massachusetts Institute of Technology
Electrical Engineering and Computer Science.