A Developmental Switch in Microglial HDAC Function
Author(s)Mathys, Hansruedi; Penney, Jay; Tsai, Li-Huei
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The epigenetic mechanisms controlling microglia functions are largely unknown. In this issue of Immunity, Datta et al. (2018) uncover surprising and distinct effects of deleting the epigenetic regulators HDAC1 and HDAC2 during microglial development versus during the course of neurodegeneration.
DepartmentPicower Institute for Learning and Memory; Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Mathys, Hansruedi et al. "A Developmental Switch in Microglial HDAC Function." Immunity 48, 3 (March 2018): 476-478 © 2018 Elsevier Inc
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