Advancements in the synthesis of distorted tricoordinate phosphorus compounds and their use as platforms in reductive chemistries

Abstract

This dissertation describes new reactivity of geometrically distorted [sigma]³ phosphorus compounds as well as attempts to synthesis new C₂v distorted [sigma]³ phosphorus compounds. Chapter two will describe the synthetic efforts towards synthesizing new [sigma]³ phosphorus compounds to provide new platforms to expand the chemistry of [sigma]³ phosphines. Chapter three presents a distorted phosphoramidate with a functionally hydridic P-H bond derived from the activation of water to generate equivalents of hydrogen. Chapter four explores the activation of both hydrazine and hydrazones by a distorted phosphoramidite and initial results in the use of these phosphoranes as platforms for hydrogen atom transfer chemistry. Chapter five presents a unique reaction in the formation of an oxazaphosphole that shows promise to allow for dearomatiztion of other aromatic substrates by a distorted phosphorus triamide. The research displayed here provides several novel approaches in the synthesis and use of [sigma]³ phosphorus compounds.