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Re-strengthening demineralized bone via tannin-iron crosslinking

Author(s)
Hart, Sawyer(Sawyer H.)
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Other Contributors
Massachusetts Institute of Technology. Department of Materials Science and Engineering.
Advisor
Niels Holten-Andersen.
Terms of use
MIT theses are protected by copyright. They may be viewed, downloaded, or printed from this source but further reproduction or distribution in any format is prohibited without written permission. http://dspace.mit.edu/handle/1721.1/7582
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Abstract
As the world population continues to age, the social and economic impacts resulting from osteoporosis will continue to rise. New treatments for the disease are needed now more than ever. Using tannin iron complexes we show that thin film deposition of the complexes are not only possible but effective at strengthening demineralized bone. Furthermore we show that by taking advantage of newly discovered tris-complexes that are able to form between tannic acid and ferrous iron ion in solution, the strengthening ability of the film increases dramatically. Specifically, we show that tannin iron tris-complex coating results in a 1062% increase in the flexural modulus for fully hydrated and demineralized bone.
Description
Thesis: S.B., Massachusetts Institute of Technology, Department of Materials Science and Engineering, 2019
 
Cataloged from PDF version of thesis.
 
Includes bibliographical references (pages [30]-[31]).
 
Date issued
2019
URI
https://hdl.handle.net/1721.1/124588
Department
Massachusetts Institute of Technology. Department of Materials Science and Engineering
Publisher
Massachusetts Institute of Technology
Keywords
Materials Science and Engineering.

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