Functional comparison of paper-based immunoassays based on antibodies and engineered binding proteins

Author(s)
Sung, Ki-Joo; Jabbour Al Maalouf, Yara; Johns, Quinlan R.; Miller, Eric Alexander; Sikes Johnson, Hadley
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Abstract
Binding protein scaffolds, such as rcSso7d, have been investigated for use in diagnostic tests; however, the functional performance of rcSso7d has not yet been studied in comparison to antibodies. Here, we assessed the analyte-binding capabilities of rcSso7d and antibodies on cellulose with samples in buffer and 100% human serum.
Date issued
2020-03
URI
https://hdl.handle.net/1721.1/125627
Department
Massachusetts Institute of Technology. Department of Chemical Engineering
Journal
Analyst
Publisher
Royal Society of Chemistry (RSC)
Citation
Sung, Ki-Joo, et al. "Functional comparison of paper-based immunoassays based on antibodies and engineered binding proteins." Analyst, 145 (2020): 2515-2519. © The Royal Society of Chemistry 2020.
Version: Final published version
ISSN
0003-2654
1364-5528
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