Blood Pressure and the Risk of Acute Kidney Injury in the ICU: Case-Control Versus Case-Crossover Designs

Author(s)
Lehman, Li-wei H.; Feng, Mengling; Yang, Yijun; Mark, Roger G
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Abstract
This chapter describes two different approaches—a case-control and a case-crossover design—to examine the effect of transient exposure of hypotension on the risk of acute kidney injury (AKI) in intensive care unit (ICU) patients. We highlight the key differences and the design rationale of these two approaches, and present preliminary findings from applying these techniques to study the relationship between hypotension and AKI using the MIMIC II database.
Date issued
2016
URI
https://hdl.handle.net/1721.1/126405
Department
Massachusetts Institute of Technology. Department of Biological Engineering
Journal
Secondary Analysis of Electronic Health Records
Publisher
Springer International Publishing
Citation
Lehman, Li-wei H.et al. "Blood Pressure and the Risk of Acute Kidney Injury in the ICU: Case-Control Versus Case-Crossover Designs." Secondary Analysis of Electronic Health Records, edited by MIT Critical Data, Springer International Publishing, 2016, 369-375. © 2016 The Author(s)
Version: Final published version
ISBN
9783319437408
9783319437422
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