A once-a-month oral contraceptive

Author(s)
Kirtane, Ameya R.; Hua, Tiffany; Hayward, Alison; Wahane, Aniket Vijay; Lopes, Aaron; ... Show more
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Abstract
Poor patient adherence to oral contraceptives is the predominant cause of failure of these therapies, leading to unplanned pregnancies that can negatively affect female health worldwide. To improve patient adherence, we developed an oral contraceptive that is administered once a month. Here, we describe the design and report in vivo characterization of a levonorgestrel-releasing gastric resident dosage form in pigs.
Date issued
2019-12
URI
https://hdl.handle.net/1721.1/126809
Department
Massachusetts Institute of Technology. Department of Chemical Engineering; Massachusetts Institute of Technology. Division of Comparative Medicine; Massachusetts Institute of Technology. Media Laboratory; Massachusetts Institute of Technology. Institute for Medical Engineering & Science; Massachusetts Institute of Technology. Department of Mechanical Engineering; Koch Institute for Integrative Cancer Research at MIT
Journal
Science Translational Medicine
Publisher
American Association for the Advancement of Science (AAAS)
Citation
Kirtane, Ameya R. et al. “A once-a-month oral contraceptive.” Science Translational Medicine, 11, 521 (December 2019): eaay2602 © 2019 The Author(s)
Version: Author's final manuscript
ISSN
1946-6242
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