Synthesis and optimization of synthetic intermediates to access C21-oxygenated aspidosperma alkaloids
Author(s)Avci, Nadide Hazal.
Massachusetts Institute of Technology. Department of Chemistry.
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Synthesis and optimization of C21-oxygenated pentacyclic aspidosperma core is described. A highly effective enzymatic resolution of a non-[beta]-branched primary alcohol (E=22) allowed rapid preparation of both enantiomeric forms of a C21-oxygenated precursor for synthesis of aspidosperma alkaloids.
Thesis: S.M., Massachusetts Institute of Technology, Department of Chemistry, 2020Cataloged from PDF of thesis.Includes bibliographical references.
DepartmentMassachusetts Institute of Technology. Department of Chemistry
Massachusetts Institute of Technology