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Regulation of alternative splicing in the rat fibronectin gene
(Massachusetts Institute of Technology, 1994)
Chromatin regulators and the determination of embryonic polarity in Drosphila
(Massachusetts Institute of Technology, 1994)
Random DNA integrations as an approach to insertional mutagenesis in the zebrafish (Brachydanio rerio)
(Massachusetts Institute of Technology, 1994)
The role of mammalian target of rapamycin complex 1 in hepatic physiology and disease
(Massachusetts Institute of Technology, 2010)
The multi-component kinase mTOR complex 1 (mTORC 1) coordinates nutrient and growth factor inputs with numerous downstream processes including protein translation, autophagy, metabolism and cell growth. We have found that ...
Chromatin structure of the inactive X chromosome
(Massachusetts Institute of Technology, 1999)
Long-term activity-induced changes in the brain : a study of translational regulation and structural plasticity
(Massachusetts Institute of Technology, 2005)
Long-lasting changes must take place in the brain to store the skills and memories that have been learned by the organism throughout its history. Long-term memory (LTM), and its cellular correlate, the late-phase of long-term ...
Control of product molecular weight in the enzymatic synthesis of a biodegradable polyester, polyhydroxybutyrate
(Massachusetts Institute of Technology, 2006)
Polyhydroxybutyrate (PHB) is a polymer accumulated by many bacterial species to store carbon and reducing equivalents. PHB is packaged intracellularly in inclusions termed "granules" that contain the polymer in an amorphous ...
The role of Cdyl and CDY in mammalian spermatogenesis
(Massachusetts Institute of Technology, 2006)
Mouse Cdyl was originally identified based on homology to the human gene CDY (Lahn and Page, 1999), which is found in four copies on the human Y chromosome (Kuroda-Kawaguchi et al., 2001). Because CDY is expressed specifically ...
Effects of aneuploidy on growth and cell cycle progression
(Massachusetts Institute of Technology, 2010)
In budding yeast, aneuploidy has a detrimental effect in cell growth and proliferation. The work presented here shows that most aneuploid yeast strains delay cell cycle entry by increasing the critical size for budding and ...
Genetic and molecular analysis of genes required for axon outgrowth in Caenorhabditis elegans
(Massachusetts Institute of Technology, 1993)