Search
Now showing items 41-42 of 42
Degradation of the E. coli small heat-shock proteins by the AAA+ protease lon : significance to protein quality-control
(Massachusetts Institute of Technology, 2010)
The refolding and elimination of damaged and aggregated proteins requires the concerted effort of several branches of the protein quality-control network. This network includes refolding chaperones, disaggregases, holdases ...
Effects of aneuploidy on growth and cell cycle progression
(Massachusetts Institute of Technology, 2010)
In budding yeast, aneuploidy has a detrimental effect in cell growth and proliferation. The work presented here shows that most aneuploid yeast strains delay cell cycle entry by increasing the critical size for budding and ...