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Characterization of the histone deacetylation activity of the yeast silencing gene SIR2
(Massachusetts Institute of Technology, 2001)
A gene's location in the genome can have profound effects on its ekpression. In Saccharomyces cerevisiae, the gene SIR2 is crucial for silencing at the HM mating type loci, the telomeres, and the rDNA array. It is also ...