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Total cost model for making sourcing decisions
(Massachusetts Institute of Technology, 2007)
This thesis develops a total cost model based on the work done during a six month internship with ABB. In order to help ABB better focus on low cost country sourcing, a total cost model was developed for sourcing decisions. ...
Allocation of engineering resources to global sites based on coordination cost and project structure
(Massachusetts Institute of Technology, 2007)
Because of the increasingly globalized world we live in, companies today are very interested in going overseas to develop and utilize global engineering resources. By doing so, they hope to take advantage of new global ...
Developing the Broad Process Excellence Program
(Massachusetts Institute of Technology, 2007)
This thesis is based on the author's experience as an intern at the Broad Institute of MIT and Harvard. The Broad Institute has been working on applying and implementing traditional manufacturing process improvement tools ...
Understanding social amplification of risk : possible impact of an avian flu pandemic
(Massachusetts Institute of Technology, 2007)
Today, stakeholders expect organizations to be able to endure external shocks. Hence, the real potential of an avian flu pandemic has many corporations developing business continuity plans for the disruptions that a pandemic ...
Process optimization in drug discovery
(Massachusetts Institute of Technology, 2007)
Novartis is one of the largest pharmaceutical companies in the world, with their research headquarters (Novartis Institutes for BioMedical Research) located in Cambridge MA. In this thesis, I explore Novartis's process for ...
Development of a design and evaluation framework for supplier cities
(Massachusetts Institute of Technology, 2007)
For companies pursuing opportunities by expanding manufacturing to new markets, one major challenge is unavoidable: identifying and developing capable, local suppliers. In developing markets suppliers often lack the cutting ...
Process improvements during production ramp-up
(Massachusetts Institute of Technology, 2007)
Raytheon Company is currently ramping up production radars for a fighter aircraft. This product is doubling production in the next year to meet customer demand; however, the program has not been able to meet the current ...
Lean implementation across value stream in main rotor blade area
(Massachusetts Institute of Technology, 2007)
The primary goal for this project was to help expand the existing capability of Sikorsky's main rotor blade business from raw material (titanium) through final assembly. The project helped to facilitate the ongoing lean ...
A core competency model for aligning information technology with business objectives
(Massachusetts Institute of Technology, 2007)
Advances in Information Technology and Information Systems delivery over the past decades have restructured industries and created enormous value. Interestingly however, research shows companies traditionally have a very ...
Optimization of preclinical profiling operations in drug discovery
(Massachusetts Institute of Technology, 2007)
In early-stage drug discovery, thousands of compounds must be tested using in vitro assays to determine their exposure and safety characteristics. This data is used to guide the selection of potential drug candidates and ...