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Now showing items 431-440 of 463
Understanding and managing profitability in a competitive environment : an application in biotechnology
(Massachusetts Institute of Technology, 2010)
For many biotech drugs, minimal competition has led to significant margins. Genentech's legacy product, however, faces intense competition from six other competitors. Competition necessitates contracting to ensure patient ...
Impact of product design choices on supply chain performance in the notebook computer industry
(Massachusetts Institute of Technology, 2010)
Intel Corporation is the world's leading manufacturer of processors for personal computers. As the company strives to maintain its leadership position in this industry, it identifies significant trends in the industry and ...
Developing biotechnology company's future positioning strategy in prefilled syringe market
(Massachusetts Institute of Technology, 2010)
The primary goal for the thesis is to develop a recommendation for Amgen's future prefilled syringe strategy related to its drug process development, supplier relationship management plan, supply and sourcing, and procurement. ...
A method for selecting and sequencing enterprise software to improve high-volume new product introduction performance
(Massachusetts Institute of Technology, 2015)
Powerful software exists to help consumer electronics enterprises manage complex product lifecycles and improve the speed with which they introduce new products to the market. While significant research exists to inform ...
Predicting adequacy of supplier responses for multi-year government contracts based on supplier performance metrics
(Massachusetts Institute of Technology, 2015)
Aerospace Company X (ACX) is a designer and manufacturer of advanced aerospace systems and its primary customer is the United States Government (USG). In order to reduce cost and minimize risk, both parties have embraced ...
Leveraging Statistical Process Control for continuous improvement of the manufacturing process
(Massachusetts Institute of Technology, 2015)
Statistical Process Control (SPC) has been applied to manufacturing processes for several decades as a means of ensuring product quality and has become a primary tool for the application of continuous improvement efforts. ...
Financial costs and benefits of sourcing from factories with different risk profiles
(Massachusetts Institute of Technology, 2015)
Li & Fung is the leading consumer goods design, development, sourcing and logistics company for global retailers and brands. Its networks cover over 15,000 suppliers and 300 offices and distribution centers in 40 economies ...
Investigating and prototyping a connected device strategy and solution for industrial equipment manufacturers
(Massachusetts Institute of Technology, 2018)
Shape Technologies makes industrial waterjet equipment that is purchased and used by customers to process a variety of materials (ranging from metal to food). To date the company has not invested in connecting their machines ...
Process Intensification of Spodoptera frugiperda (Sf) Cell Growth via Multi-Parallel Bioreactor System
(Massachusetts Institute of Technology, 2020)
The objective of this project is to improve the yield of the fed-batch manufacturing process for the production of Flublok influenza vaccine, which was approved by the FDA in 2018. In short, Spodoptera frugiperda (SF+) ...
Enabling effective lifecycle management of manufacturing facilities with enhanced decision making processes
(Massachusetts Institute of Technology, 2017)
As a global manufacturing company, Company X has built up an extensive and varied portfolio of manufacturing facilities. These facilities vary greatly in capability, age, and performance. This creates difficulties in ...