Search
Now showing items 1-4 of 4
A central composite design to investigate antibody fragment production by Pichia pastoris
(Massachusetts Institute of Technology, 2005)
This study aims to investigate the relationships between growth parameters (agitation, glycerol concentration, salt concentration) and responses (biomass, growth rate, protein expression), by a 3-factor-3-level central ...
Investigation of growth factors and cytokines that suppress adult stem cell asymmetric cell kinetics
(Massachusetts Institute of Technology, 2005)
Adult stem cells are potentially useful in many biomedical applications that can save lives and increase the quality of a patient's life, such as tissue engineering, cell replacement, and gene therapy. However, these ...
Dendritic cell maturation and activation via RNA/DNA danger signals : co-delivery of protein antigen with siRNA or CpG DNA
(Massachusetts Institute of Technology, 2005)
Traditional vaccines consisting of live attenuated pathogens or inactivated toxins cannot be readily applied to the more challenging diseases of the present e.g. hepatitis C and the human immunodeficiency virus. As such, ...
Regulation of apoptosis in human cancer cells
(Massachusetts Institute of Technology, 2005)
Nitric oxide is postulated to protect cancer cells from the death-inducing effects of tumour necrosis factor alpha by S-nitrosating the active site cysteines, inhibiting cleavage of caspase-9. We aimed to test this hypothesis ...