Search
Now showing items 1-10 of 14
Mergers and acquisitions in the medical device industry
(Massachusetts Institute of Technology, 2007)
Mergers and acquisitions in the Medical Device Industry are the primary mode of exit for early stage companies. The focus of this thesis is to examine factors which influence the value of these M&A transactions from the ...
Proteomics for cancer biomarker discovery
(Massachusetts Institute of Technology, 2007)
Background: If we are to successfully treat cancer, we must understand the biologic underpinnings in conjunction with early diagnosis. Genome-wide expression studies have advanced the research of many cancers. Nevertheless, ...
Enhancing productivity through effective collaborations : the barriers and enablers of collaboration within geographic bioclusters
(Massachusetts Institute of Technology, 2007)
Increasing competition and specialization of firms in the life sciences industry has led to recognition of the need for collaboration. Bioclusters, the co-location of life sciences entities in a specific geographic area, ...
What future physicians want : a comparative analysis of the perception of medical students and pharmaceutical industry executives regarding the future of pharmaceutical sales
(Massachusetts Institute of Technology, 2007)
The leading publicly traded pharmaceutical companies ("Big Pharma) in the US are facing a commercial crisis - their sales structure collectively consisting of more than 100,000 pharmaceutical sales representatives, originally ...
Assessing decision inputs in drug development between small, early stage companies and big pharma : is there is a difference?
(Massachusetts Institute of Technology, 2007)
The pipeline productivity challenge facing large, publicly traded pharmaceutical companies, collectively referred to as "Big Pharma," is well known. The unprecedented success Big Pharma achieved over the past few decades ...
Investment performance of life-science venture capital investment funds, persistence, and subsector analysis
(Massachusetts Institute of Technology, 2007)
Venture capital investment performance data and performance attribution are not typically published. Venture investors articulate (and sell to LPs) conflicting strategies; the popular business literature and culture is ...
Factors influencing the time for FDA review of medical devices
(Massachusetts Institute of Technology, 2007)
Companies must receive marketing authorization by the Food and Drug Administration (FDA) before they can begin commercial distribution of a new type of medical device in the United States. The premarket approval application ...
Value creation through modernizing Chinese medicine
(Massachusetts Institute of Technology, 2007)
My first hypothesis in this thesis is that there is significant value vested in traditional Chinese medicine that can be captured by converting them into ethical drugs through scientific analysis, screening and validation. ...
Best care practices in anesthesiology : development and evaluation of an electronic feedback system to improve physician compliance with evidence-based practices
(Massachusetts Institute of Technology, 2007)
Recently, hospitals, regulatory agencies, and insurers have renewed their focus on improving patient care and safety. Outcomes based measures are being utilized and hospitals are being asked to report on whether patients ...
Mathematical and mechanical modeling of vaso-occlusion in sickle cell disease
(Massachusetts Institute of Technology, 2007)
Vaso-occlusive crises cause most of the morbidity and mortality associated with sickle cell disease. The proximal causes of these occlusive events are not well understood. The risks and consequences of vaso-occlusion however ...