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Developing global inventory and resupply forecasting policies for the vaccines industry
(Massachusetts Institute of Technology, 2011)
Appropriate inventory management is important for many businesses throughout the world. For the vaccines industry, appropriate inventory policies impact both the business' profitability and people's lives. An optimal policy ...
Lean transformation and relocation of jet engine assembly operations
(Massachusetts Institute of Technology, 2011)
As part of continuing lean transformation efforts at Pratt & Whitney, the Middletown Engine Center has turned its focus on the GP7000 turbofan engine as a target for lean implementation. Projected increases in GP7000 ...
Optimization of shake inspections
(Massachusetts Institute of Technology, 2011)
The Boeing 737 program has recently announced an increase in the production rate from 31.5 airplanes per month to 35 airplanes per month. Throughout the production value stream, opportunities to improve quality and reduce ...
Corporate sustainability assessment methodology
(Massachusetts Institute of Technology, 2011)
Sustainability is a vague concept specifically in the context of a corporate world. There are numerous definitions for corporate sustainability and just as many ways of evaluating it. This work attempts to define, structure ...
Forecasting and planning for a multi-product seasonal production facility
(Massachusetts Institute of Technology, 2011)
With increasing cost pressure on commodity vaccine products, Novartis Vaccines & Diagnostics is continually looking for ways to improve operating efficiencies and decrease costs. As the largest drug product manufacturing ...
New product demand forecasting and distribution optimization : a case study at Zara
(Massachusetts Institute of Technology, 2011)
The problem of optimally distributing new products is common to many companies and industries. This thesis describes how this challenge was addressed at Zara, a leading retailer in the "fast fashion" industry. The thesis ...
Cost modeling for monoclonal antibody manufacturing
(Massachusetts Institute of Technology, 2011)
The Novartis BioPharmOps division is responsible for manufacturing large molecule products, including monoclonal antibodies, for late stage clinical trials and commercial sales. The BioPharmOps site in Huningue, France is ...