| dc.contributor.author | Sivanand, Sharanya | |
| dc.contributor.author | Vander Heiden, Matthew G | |
| dc.date.accessioned | 2022-02-07T14:03:25Z | |
| dc.date.available | 2021-10-27T19:53:29Z | |
| dc.date.available | 2022-02-07T14:03:25Z | |
| dc.date.issued | 2020-02 | |
| dc.identifier.issn | 1878-3686 | |
| dc.identifier.uri | https://hdl.handle.net/1721.1/133548.2 | |
| dc.description.abstract | © 2020 Elsevier Inc. Metabolic pathways must be adapted to support cell processes required for transformation and cancer progression. Amino acid metabolism is deregulated in many cancers, with changes in branched-chain amino acid metabolism specifically affecting cancer cell state as well as systemic metabolism in individuals with malignancy. This review highlights key concepts surrounding the current understanding of branched-chain amino acid metabolism and its role in cancer. | en_US |
| dc.language.iso | en | |
| dc.publisher | Elsevier BV | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1016/J.CCELL.2019.12.011 | en_US |
| dc.rights | Creative Commons Attribution-NonCommercial-NoDerivs License | en_US |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | en_US |
| dc.source | PMC | en_US |
| dc.title | Emerging Roles for Branched-Chain Amino Acid Metabolism in Cancer | en_US |
| dc.type | Article | en_US |
| dc.contributor.department | Koch Institute for Integrative Cancer Research at MIT | |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Biology | |
| dc.relation.journal | Cancer Cell | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dc.date.updated | 2021-08-03T16:36:13Z | |
| dspace.orderedauthors | Sivanand, S; Vander Heiden, MG | en_US |
| dspace.date.submission | 2021-08-03T16:36:14Z | |
| mit.journal.volume | 37 | en_US |
| mit.journal.issue | 2 | en_US |
| mit.license | PUBLISHER_CC | |
| mit.metadata.status | Authority Work Needed | en_US |
