Magnetic Multivalent Trehalose Glycopolymer Nanoparticles for the Detection of Mycobacteria

Author(s)
Chen, Xuan; Wu, Bin; Jayawardana, Kalana W.; Hao, Nanjing; Jayawardena, H. Surangi N.; ... Show more
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Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/
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Abstract
A multivalent trehalose-grafted poly(lactic acid) is synthesized and encapsulated with iron oxide magnetic nanoparticles. The magnetic micelles interact with Mycobacterium smegmatis to form orange clusters. Very little particle interaction is found on Staphylococcus epidermidis 35984 or Escherichia coli ORN 208. The presented new approach to the detection of mycobacteria does not require molecular biology reagents or sophisticated instruments.
Date issued
2016-06
URI
https://hdl.handle.net/1721.1/134658.2
Department
Koch Institute for Integrative Cancer Research at MIT
Journal
Advanced Healthcare Materials
Publisher
Wiley
Citation
Chen, X., et al. "Magnetic Multivalent Trehalose Glycopolymer Nanoparticles for the Detection of Mycobacteria." Adv Healthc Mater (2016).
Version: Author's final manuscript
ISSN
2192-2640
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21721.1/134658.2*2022-04-14T19:21:21ZPublication information verified/added.
11721.1/1346582021-10-27T20:06:03Z

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