The Global Configuration of Visual Stimuli Alters Co-Fluctuations of Cross-Hemispheric Human Brain Activity
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9756.full.pdf
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1.95 MB
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Author(s)
Nasr, Shahin
Kleinfeld, David
Polimeni, Jonathan
Date Issued
November 24, 2021
Journal
Journal of Neuroscience
Publisher
Society for Neuroscience
Citation
Shahin Nasr, David Kleinfeld, Jonathan R. Polimeni, Journal of Neuroscience 24 November 2021, 41 (47) 9756-9766.
Version
Final published version
Abstract
We tested how a stimulus gestalt, defined by the neuronal interaction between local and global features of a stimulus, is represented within human primary visual cortex (V1). We used high-resolution fMRI, which serves as a surrogate of neuronal activation, to measure co-fluctuations within subregions of V1 as (male and female) subjects were presented with peripheral stimuli, each with different global configurations. We found stronger cross-hemisphere correlations when fine-scale V1 cortical subregions represented parts of the same object compared with different objects. This result was consistent with the vertical bias in global processing and, critically, was independent of the task and local discontinuities within objects. Thus, despite the relatively small receptive fields of neurons within V1, global stimulus configuration affects neuronal processing via correlated fluctuations between regions that represent different sectors of the visual field.
Subjects
binding problem
feature conjunction
high-resolution fMRI
primary visual cortex (V1)
spontaneous activity Significance Statement
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1523/JNEUROSCI.3214-20.2021
