Instrumentation to characterize needle insertion into biological tissue
Author(s)Chan, Wilson (Wilson Sian Chew), 1976-
Massachusetts Institute of Technology. Dept. of Mechanical Engineering.
Ian W. Hunter.
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The Transdermal Drug Delivery Project in the BioInstrumentation Laboratory involves the design of a device to deliver drugs through the human skin using micro needles. It is crucial to characterize the insertion of micro needles into biological tissues. Hence, instrumentation will be designed and fabricated for the characterization of micro needle insertion. This thesis focuses on the design and fabrication of such instrumentation. The instrument is multi-modal, multi-axis, mobile and compact. It is capable of precise insertion positioning and acquiring accurate insertion force data. Characterization of micro needle insertion into biological tissues is done successfully using the data acquired by this instrument and an existing physical force model.
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2002.Includes bibliographical references (leaves 52-53).
DepartmentMassachusetts Institute of Technology. Dept. of Mechanical Engineering.; Massachusetts Institute of Technology. Department of Mechanical Engineering
Massachusetts Institute of Technology