Instrumentation to characterize needle insertion into biological tissue

Author(s)
Chan, Wilson (Wilson Sian Chew), 1976-
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Massachusetts Institute of Technology. Dept. of Mechanical Engineering.
Advisor
Ian W. Hunter.
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Abstract
The Transdermal Drug Delivery Project in the BioInstrumentation Laboratory involves the design of a device to deliver drugs through the human skin using micro needles. It is crucial to characterize the insertion of micro needles into biological tissues. Hence, instrumentation will be designed and fabricated for the characterization of micro needle insertion. This thesis focuses on the design and fabrication of such instrumentation. The instrument is multi-modal, multi-axis, mobile and compact. It is capable of precise insertion positioning and acquiring accurate insertion force data. Characterization of micro needle insertion into biological tissues is done successfully using the data acquired by this instrument and an existing physical force model.
Description
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2002.
 
Includes bibliographical references (leaves 52-53).
 
Date issued
2002
URI
http://hdl.handle.net/1721.1/17541
Department
Massachusetts Institute of Technology. Department of Mechanical Engineering
Publisher
Massachusetts Institute of Technology
Keywords
Mechanical Engineering.
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