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dc.contributor.authorJensen, Kyle
dc.contributor.authorStephanopoulos, Gregory
dc.date.accessioned2005-12-16T14:33:45Z
dc.date.available2005-12-16T14:33:45Z
dc.date.issued2006-01
dc.identifier.urihttp://hdl.handle.net/1721.1/30381
dc.description.abstractThis work introduces two unconventional applications for sequence alignment algorithms outside the domain of bioinformatics: handwriting recognition and speech recognition. In each application we treated data samples, such as the path of a and written pen stroke, as a protein sequence and use the FastA sequence alignment tool to classify unknown data samples, such as a written character. That is, we handle the handwriting and speech recognition problems like the protein annotation problem: given a sequence of unknown function, we annotate the sequence via sequence alignment. This approach achieves classification rates of 99.65% and 93.84% for the handwriting and speech recognition respectively. In addition, we provide a framework for applying sequence alignment to a variety of other non–traditional problems.en
dc.description.sponsorshipSingapore-MIT Alliance (SMA)en
dc.format.extent84123 bytes
dc.format.mimetypeapplication/pdf
dc.language.isoenen
dc.relation.ispartofseriesMolecular Engineering of Biological and Chemical Systems (MEBCS)en
dc.subjectMachine learningen
dc.subjectbioinformaticsen
dc.subjectamino acidsen
dc.subjectprotein sequencesen
dc.subjectsequence alignmenten
dc.subjectFastAen
dc.subjectvoiceen
dc.subjectdynamic programmingen
dc.subjecthandwritingen
dc.titleBioinformatics and Handwriting/Speech Reconition: Uncoventional Applications of Similarity Search Toolsen
dc.typeArticleen


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