dc.contributor.author | Jensen, Kyle | |
dc.contributor.author | Stephanopoulos, Gregory | |
dc.date.accessioned | 2005-12-16T14:33:45Z | |
dc.date.available | 2005-12-16T14:33:45Z | |
dc.date.issued | 2006-01 | |
dc.identifier.uri | http://hdl.handle.net/1721.1/30381 | |
dc.description.abstract | This work introduces two unconventional applications for sequence alignment algorithms outside the domain of bioinformatics: handwriting recognition and speech recognition. In each application we treated data samples, such as the path of a and written pen stroke, as a protein sequence and use the FastA sequence alignment tool to classify unknown data samples, such as a written character. That is, we handle the handwriting and speech recognition problems like the protein annotation problem: given a sequence of unknown function, we annotate the sequence via sequence alignment. This approach achieves classification rates of 99.65% and 93.84% for the handwriting and speech recognition respectively. In addition, we provide a framework for applying sequence alignment to a variety of other non–traditional problems. | en |
dc.description.sponsorship | Singapore-MIT Alliance (SMA) | en |
dc.format.extent | 84123 bytes | |
dc.format.mimetype | application/pdf | |
dc.language.iso | en | en |
dc.relation.ispartofseries | Molecular Engineering of Biological and Chemical Systems (MEBCS) | en |
dc.subject | Machine learning | en |
dc.subject | bioinformatics | en |
dc.subject | amino acids | en |
dc.subject | protein sequences | en |
dc.subject | sequence alignment | en |
dc.subject | FastA | en |
dc.subject | voice | en |
dc.subject | dynamic programming | en |
dc.subject | handwriting | en |
dc.title | Bioinformatics and Handwriting/Speech Reconition: Uncoventional Applications of Similarity Search Tools | en |
dc.type | Article | en |