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Linear Thermodynamics of Rodlike DNA Filtration

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Show simple item record Li, Zirui Liu, Guirong Chen, Yuzong Wang, Jian-Sheng Hadjiconstantinou, Nicolas Cheng, Y. Han, J. 2007-01-31T14:43:06Z 2007-01-31T14:43:06Z 2007-01
dc.description.abstract Linear thermodynamics transportation theory is employed to study filtration of rodlike DNA molecules. Using the repeated nanoarray consisting of alternate deep and shallow regions, it is demonstrated that the complex partitioning of rodlike DNA molecules of different lengths can be described by traditional transport theory with the configurational entropy properly quantified. Unlike most studies at mesoscopic level, this theory focuses on the macroscopic group behavior of DNA transportation. It is therefore easier to conduct validation analysis through comparison with experimental results. It is also promising in design and optimization of DNA filtration devices through computer simulation. en
dc.description.sponsorship Singapore-MIT Alliance (SMA) en
dc.format.extent 231148 bytes
dc.format.mimetype application/pdf
dc.language.iso en en
dc.relation.ispartofseries Computational Engineering (CE) en
dc.subject DNA en
dc.subject Electrophoresis en
dc.subject Filtration en
dc.subject Entropy Barrier en
dc.subject Transportation en
dc.subject Linear Thermodynamics en
dc.title Linear Thermodynamics of Rodlike DNA Filtration en
dc.type Article en

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