Browsing Singapore-MIT Alliance (SMA) by Author "Lee, Lai Yeng"
Now showing items 1-3 of 3
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Fabrication of Controlled Release Devices Using Supercritical Antisolvent Method
Lee, Lai Yeng; Smith, Kenneth A.; Wang, Chi-Hwa (2005-01)In this study, the supercritical antisolvent with enhanced mass transfer method (SASEM) is used to fabricate micro and nanoparticles of biocompatible and biodegradable polymer PLGA (poly DL lactide co glycolic acid). This ... -
Fabrication of Micro and Nanoparticles of Paclitaxel-loaded Poly L Lactide for Controlled Release using Supercritical Antisolvent Method: Effects of Thermodynamics and Hydrodynamics
Lee, Lai Yeng; Smith, Kenneth A.; Wang, Chi-Hwa (2006-01)This paper presents the fabrication of controlled release devices for anticancer drug paclitaxel using supercritical antisolvent method. The thermodynamic and hydrodynamic effects during supercritical antisolvent process ... -
Micro-porous Paclitaxel-Loaded PLGA Foams -- a New Implant Material for Controlled Release of Chemotherapeutic Agents
Lee, Lai Yeng; Wang, Chi Hwa; Smith, Kenneth A. (2007-01)Supercritical gas foaming using CO₂ was used to fabricate blank poly DL lactide-co-glycolide (PLGA) micro-porous foams. Paclitaxel-loaded PLGA foams were also produced for the first time using a modification of the ...