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Targeted Stimuli-Responsive Dextran Conjugates for Doxorubicin Delivery to Hepatocytes
A targeted, stimuli-responsive, polymeric drug delivery vehicle has been developed to help alleviate the severe side-effects caused by narrow therapeutic window drugs. Doxorubicin, a commonly used chemotherapeutic agent ...
NIR-Sensitive Au-Au₂S Nanoparticles for Drug Delivery
Near IR (NIR) sensitive Au-Au₂S nanoparticles were prepared by mixing HAuCl₄ and Na₂S in aqueous solutions. An anti-tumor drug, cis-platin, was adsorbed onto Au-Au₂S nanoparticle surface via the 11-mercaptoundecanoic acid ...
Pharmaceutical Properties of Nanoparticulate Formulation Composed of TPGS and PLGA for Controlled Delivery of Anticancer Drug
A suitable management of the pharmaceutical property is needed and helpful to design a desired nanoparticulate delivery system, which includes the carrier nature, particle size and size distribution, morphology, surfactant ...
Glucose-Sensitive Nanoparticles for Controlled Insulin Delivery
A novel reverse microemulsion (RM) mediated synthesis of glucose-responsive nanoparticles was developed for controlled insulin delivery. Nanoparticles were constructed using a model system comprised of dextran, poly(α-1,6 ...
Delivery of Etanidazole to Brain Tumor from PLGA Wafers
This paper presents the computer simulation results on the delivery of Etanidazole (radiosensitiser) to the brain tumor and examines several factors affecting the delivery. The simulation consists of a 3D model of tumor ...