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Over Expression of the CMP-sialic Acid Transporter in Chinese Hamster Ovary Cells Leads to Increased Sialylation
(2005-01)
Most glyco-engineering approaches used to improve quality of recombinant glycoproteins involve the manipulation of glycosyltransferase and/or glycosidase expression. We investigated whether the over expression of nucleotide ...
Cell-line Engineering of Chinese Hamster Ovary Cells for Low-temperature Culture
(2005-01)
Developments in mammalian cell culture and recombinant technology has allowed for the production of recombinant proteins for use as human therapeutics. Mammalian cell culture is typically operated at the physiological ...
Variability in the Stability and Productivity of Transfected Genes in Chinese Hamster Ovary (CHO) cells
(2005-01)
In the field of biologics production, productivity and stability of the transfected gene of interest are two very important attributes that dictate if a production process is viable. To further understand and improve these ...