Browsing Molecular Engineering of Biological and Chemical Systems (MEBCS) by Author "Ajikumar, Parayil Kumaran"
Now showing items 1-6 of 6
-
Deposition of Thin Films of Biocompatible Calcium Carbonate via Template-Driven Mineralization
Ajikumar, Parayil Kumaran; Lakshminarayanan, Rajamani; Valiyaveettil, Suresh (2004-01)Natural bone is a composite of collagen based hydrogel and inorganic dahilite crystals. The unusual combination of a hard inorganic material and an underlying elastic hydrogel network endows native bone with unique mechanical ... -
Design, Fabrication and Functional Analysis of a New Protein Array Based on ssDNA-based Assembly
Ajikumar, Parayil Kumaran; Ng, Jin Kiat; Tang, Yew Chung; Lee, Jim Yang; Stephanopoulos, Gregory; e.a. (2006-01)In the post genomic era, proteomics has enormous potential in biology and medicine. Among the various bioanalytical tools developed, protein microarray is one of the recent advancements which offer high throughput profiling ... -
Designer peptides to understand the mineralization of calcium salts
Ajikumar, Parayil Kumaran; Lakshminarayanan, Rajamani; Valiyaveettil, Suresh; Kini, R. Manjunatha (2003-01)Recently, we reported the extraction, purification and amino acid sequence of ansocalcin, the major goose eggshell matrix protein. In vitro studies showed that ansocalcin induces spherical calcite crystal aggregates. We ... -
Eggshell Matrix Protein Mimetics: Elucidation of Molecular Mechanism of Goose Eggshell Calcification using Designed Peptides
Ajikumar, Parayil Kumaran; Lakshminarayanan, Rajamani; Valiyaveettil, Suresh; Kini, R. Manjunatha (2004-01)Model peptides were designed, synthesized and conducted a detailed structure-property study to unravel the molecular mechanism of goose eggshell calcification. The peptides were designed based on the primary structural ... -
Protein Microarray: "Theory" to "Real Practice"
Ng, Jin Kiat; Ajikumar, Parayil Kumaran; Lee, Jim Yang; Stephanopoulos, Gregory; Too, Heng-Phon (2005-01)Fueled by ever-growing genomic information and rapid developments of proteomics–the large scale analysis of proteins and mapping its functional role has become one of the most important disciplines for characterizing complex ... -
SCAPA (Spacially Addressable Protein Array) – a Novel Protein Array for the Differential Profiling of Ligand-receptor Induced Signalling
Ajikumar, Parayil Kumaran; Ng, Jin Kiat; Lee, Jim Yang; Stephanopoulos, Gregory; Too, Heng-Phon (2005-01)While protein microarray technology has been successful in demonstrating its usefulness for large scale high-throughput proteome profiling, performance of antibody/antigen microarrays has been only moderately productive. ...