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A combined microfluidic/dielectrophoretic microorganism concentrator

Author(s)
Gadish, Nitzan
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Massachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science.
Advisor
Joel Voldman.
Terms of use
M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. http://dspace.mit.edu/handle/1721.1/7582
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Abstract
This thesis presents the development of a high-throughput microfluidic microorganism concentrator for pathogen detection applications. Interdigitated electrodes lining the bottom of the channel use positive dielectrophoretic forces to trap particles. A passive mixer is used to circulate the liquid in the channel, transporting particles to within the trapping region of the electrodes. Samples are extracted and their concentrations measured using a spectrophotometer. Concentration enhancements up to 40x at 500 gl/min flowrate using polystyrene microspheres and up to 10x at 100 gll/min flowrate using B. subtilis spores are achieved.
Description
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2005.
 
Includes bibliographical references (p. 71-72).
 
Date issued
2005
URI
http://hdl.handle.net/1721.1/36758
Department
Massachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science.
Publisher
Massachusetts Institute of Technology
Keywords
Electrical Engineering and Computer Science.

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  • Electrical Engineering and Computer Sciences - Master's degree
  • Electrical Engineering and Computer Sciences - Master's degree

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