A combined microfluidic/dielectrophoretic microorganism concentrator

Author(s)
Gadish, Nitzan
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Massachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science.
Advisor
Joel Voldman.
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Abstract
This thesis presents the development of a high-throughput microfluidic microorganism concentrator for pathogen detection applications. Interdigitated electrodes lining the bottom of the channel use positive dielectrophoretic forces to trap particles. A passive mixer is used to circulate the liquid in the channel, transporting particles to within the trapping region of the electrodes. Samples are extracted and their concentrations measured using a spectrophotometer. Concentration enhancements up to 40x at 500 gl/min flowrate using polystyrene microspheres and up to 10x at 100 gll/min flowrate using B. subtilis spores are achieved.
Description
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2005.
 
Includes bibliographical references (p. 71-72).
 
Date issued
2005
URI
http://hdl.handle.net/1721.1/36758
Department
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Publisher
Massachusetts Institute of Technology
Keywords
Electrical Engineering and Computer Science.
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