Effect of Column Inlet and Outlet Geometry on Large-scale HPLC

dc.contributor.author	Tan, S.N.
dc.contributor.author	Khoo, Boo Cheong
dc.date.accessioned	2003-11-17T17:25:45Z
dc.date.available	2003-11-17T17:25:45Z
dc.date.issued	2003-01
dc.identifier.uri	http://hdl.handle.net/1721.1/3700
dc.description.abstract	The separating characteristics of high performance liquid chromatography (HPLC) columns, measured in terms of the height equivalent of a theoretical plate (HETP) and skewness of the eluted peak, are investigated using computational fluid dynamics (CFD). Gradually expanding and contracting sections are introduced at the inlet and outlet, respectively, in columns with and without frits and their performance was compared with that of the conventional columns without expanding and contracting regions.	en
dc.description.sponsorship	Singapore-MIT Alliance (SMA)	en
dc.format.extent	384637 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en_US
dc.relation.ispartofseries	High Performance Computation for Engineered Systems (HPCES);
dc.subject	column efficiency	en
dc.subject	computational fluid dynamics	en
dc.subject	FLUENT	en
dc.subject	Frit quality	en
dc.subject	liquid chromatography	en
dc.title	Effect of Column Inlet and Outlet Geometry on Large-scale HPLC	en
dc.type	Article	en